MOTHER-podcast with Karina Vazirova MOTHER-podcast

Our bodies are a byproduct of millions of years of evolution. MOTHER-nature, as the most iterative technologist, has orchestrated the female form - from the menstrual cycles to orgasms, from pregnancies to menopause. But, how? Why did our biology evolve to be exactly the way it is today?
Deena Emera, PhD is an evolutionary geneticist, author, educator and senior scientist at the Buck Institute for Research on Aging. In her latest hit book "A Brief History of the Female Body" she draws on her vast expertise as a biologist, her experience as a mother of four children, and her love of teaching to look far into our evolutionary past, illuminating how and, more importantly, why the female form has transformed over millions of years and its effects on women's health.
(0:00) Intro
(01:10) Unexpected benefits of knowing our evolutionary biology
(04:40) Mother-child conflict during and after pregnancy
(15:43) Evolutionary purpose of the menstrual cycle
(18:32) The endometrium as an embryo sensor
(23:42) How studying the endometrium can help cure cancer
(25:22) Female orgasm from the evolutionary perspective
(33:02) Menopause as a rare evolutionary trait
(38:12) Delaying menopause: current state of the art and goals
(42:06) Reproductive choice
(44:16) The dynamic between biological and technological evolution
(47:34) Current tensions between females and males
Links:
Deena's book "A Brief History of the Female Body" - https://www.amazon.co.uk/Brief-History-Female-Body-Evolutionary-ebook/dp/B0BB8SCVDQ
Deena's Boston Globe article "Reproductive choice is at the core of being a female mammal" - https://www.bostonglobe.com/2022/07/20/opinion/reproductive-choice-is-core-being-female-mammal/




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Could psychedelics start a new era in women's holistic health?
Dr. Grace Blest-Hopley is a Neuroscientist with 10 years of experience researching cannabis, cannabinoids, and psychedelics. She is the founder of Hystelica - the first research organisation in the world focused on understanding women's biology for safe and effective psychedelic use. Grace currently serves as the Chief Scientific Officer at NWPharma Tech and is also the Research Director at Heroic Hearts Project, a charity connecting military veterans with mental trauma to psychedelic therapy options: ayahuasca, psilocybin, and ketamine.
In this episode, you'll hear about the incredible potential of psychedelics in women's health.
(0:00) Intro
(01:16) What is a psychedelic?
(02:33) Why is it important to study psychedelics for women separately?
(11:24) Safety of psychedelic use for women
(13:50) Hystelica's research into psychedelics for women
(15:42) Microdosing and menopause
(19:32) Anti-inflammatory properties of psychedelics
(21:31) Evidence that women process trauma differently
(23:59) The exact mechanism between trauma and disease
(28:44) Neuroscientist's definition of trauma
(31:11) Women in combat and PTSD
(33:52) How indigenous women use of psychedelics
(36:39) Big goal in psychedelics for women's health: Big Data
(38:56) How can anyone participate in Hystelica's research?
Links:
Grace's LinkedIn - https://www.linkedin.com/in/grace-blest-hopley-msc-akc
Hystelica - https://www.hystelica.com/
Hystelica's Instagram - https://www.instagram.com/wearehystelica/
Heroic Hearts - https://www.heroicheartsuk.com/

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How does the female body respond to space?
Dr. Shawna Pandya is a scientist-astronaut candidate with Project PoSSUM, physician, aquanaut, speaker, martial artist, advanced diver, skydiver, pilot-in-training, VP Immersive Medicine with Luxsonic Technologies and Fellow of the Explorers’ Club. She is also the Director of the PosSUM Space Medicine Group and Chief Instructor of the PoSSUM Operational Space Medicine Group. Shawna holds degrees in neuroscience (BSc Hons. Neuroscience, University of Alberta), space (MSc Space Studies, International Space University), entrepreneurship (Graduate Studies Program, Singularity University) and medicine (MD, University of Alberta), and is currently completing a fellowship in Wilderness Medicine (Academy of Wilderness Medicine).
Today, women constitute approximately 12% of all astronauts. How has being in space affected their menstrual cycles, reproductive health, ovarian longevity, bone density, and hormones?
This is important to think about now, because as Shawna put it: "We are going to space for humanity so we need to do it with all of humanity."
A shared and visionary goal within the space industry is for humans to live and thrive across multiple planets. Human ingenuity is incredible so if someone is dreaming about it, it will eventually happen. And when it does - will we be able to reproduce in space? What will just thinking about it teach us about life and pregnancy? Scientists and entrepreneurs are already looking for answers while you are reading this sentence! From figuring out how to have intercourse in space to exploring whether it is possible to conceive a baby out there.
This spaceship is launching. Join me and Shawna in this episode to get on it ;)
(00:00) Intro
(01:25) What does it feel like to be in space?
(04:15) Why are humans travelling into space? What is the goal?
(07:58) The golden age of commercial space travel is now!
(10:26) How do female astronauts experience space travel?
(12:17) Is it too early to care about female health in space?
(15:58) What happens to the human body in space?
(25:48) Can humans reproduce in space?
(35:41) What's your take on artificial wombs?
(38:10) What's the effect of space travel on ovarian reserve?
(42:27) What's the effect on menopause and perimenopause?
(44:39) Could there be health benefits of going into space?
(46:24) Doing innovative science experiments in space
(49:06) 3D printing in space
(50:28) Women's health research in the space environment
(53:13) Key ethical health considerations about the future of space exploration
(54:27) Shawna's plans for 2024 and closing thoughts
Links:
Shawna's Linkedin - https://www.linkedin.com/in/shawnapandya
Shawna's Twitter - https://twitter.com/shawnapandya
Shawna" Instagram - https://www.instagram.com/shawnapandya

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What if we could delay the age of menopause?
Staša Stanković, PhD is a geneticist and bioinformatician with a PhD in Reproductive Genomics from the University of Cambridge. She focuses on deciphering genetic architecture of reproductive ageing and fertility, and their link to health outcomes in women. This work led to the discovery of genetic signals that influence the age women begin menopause and the first evidence of the ability to, through gene manipulation, extend reproductive lifespan and improve fertility in mice, thus paving the path towards first genetic test for the prediction of menopause time and next-generation therapeutics for ovary-centric disorders in humans.
(00:00) Stasa's early experiences with womanhood
(03:32) Intro to genomics in women's health
(05:33) Historical neglect in women's health research
(07:51) Delaying motherhood vs. female biology
(09:39) Redefining menopause as "reproductive ageing"
(13:54) The difference between reproductive ageing in men v. women
(14:39) Menopausal timing variation and early menopause
(16:54) How the age of menopause can help fertility planning
(19:30) How reproductive age relates to our longevity and health
(23:02) Epigenetic factors that influence menopause timing
(24:49) Mother's diet during pregnancy can influence the menopause timing of the baby
(26:46) How genomic medicine is revolutionizing reproductive ageing
(30:08) Insights from DNA analysis of 200,000 women
(39:45) How ancestry can influence menopausal timing
(42:52) Can we delay menopause today?
(46:15) Using CRISPR technology to delay menopause in mice
(48:49) The goal of delaying menopause
(59:23) Why should we "mess" with our biology?
Links:
Staša's Linkedin - https://www.linkedin.com/in/stasa-stankovic-93723a137

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Are we entering a new dawn of sexual liberation?
Aella is a model, camgirl, escort and internet personality. She has been one of the highest-earning models on OnlyFans, making up to $100,000/month. But what makes her a truly fascinating human is her highly analytical, curious and creative mind. Aella realised that no one was asking questions about sexual preferences in a systemic way. So she taught herself data science and created The Big Kink Survey which went viral online and has been filled out by over 1 Million people. The survey is now the most comprehensive dataset on fetishes, kinks, and sexual preferences.
Naturally, I was curious: What are women into according to the survey results? Turns out, there are fascinating patterns!
In this episode, Aella explained that fetishes are actually on a spectrum, just like sexual preferences. She talked about her "How to Be Good in Bed" blog series for men, her view on the future of the sex profession, the pros and cons of OnlyFans, her hot take on feminism, artificial wombs, psychedelics and much much more. 
(00:00) Intro
(01:12) The Big Kink Survey
(01:28) Understanding fetishes
(03:48) Women's fetishes
(12:08) Women's preference for violent porn
(16;51) Aella's sex parties
(18:51) Sexuality and creativity
(19:53) Aella's experience with social shame
(25:30) Spirituality
(30:32) OnlyFans trends
(32:20) Non-nude cam girls
(33:02) Male group psychology on OnlyFans
(34:04) Sex work and safety
(34:54) Escorting
(36:36) Aella's "Date Me" application form
(42:46) How Aella got into sex research
(43;59) New exciting survey Aella is working on
(48:03) Artificial Wombs and Feminism
Links:
Aella's Website - www.knowingless.com
Blog & Research - https://aella.substack.com/
To take the The Big Kink Survey - https://www.guidedtrack.com/programs/u4m797m/run
Twitter - www.twitter.com/aellagirl

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Could psychedelics be a game changer for women's health?
Nina Patrick, PhD - Head of Innovation at the Champalimaud Foundation Center of the Unknown in Lisbon, a state-of-the-art research facility working on cutting-edge technology in oncology and neuroscience. Her popular newsletter, Nina's Notes, is a bite-sized editorial on science & health topics like longevity, psychedelics, web3, space travel, and the future of medicine.
In this episode, we discussed the latest research and the legality of psychedelic therapy (which is different from taking psychedelics recreationally). Nina explained how psychedelics work on the receptors in the brain, and we discussed how psychedelics can have a huge impact on women’s health - from postpartum depression to eating disorders, to menopause.
If you are interested in this topic and are looking for a credible overview - this episode is for you.
(0:00) - Intro
(1:14) - What is a psychedelic?
(2:30) - Psychedelics and the brain barrier
(3:50) - Examples of psychedelic therapy & ketamine clinics
(07:50) - Legality of Psychedelics
(12:36) - MDMA for treatment of PTSD
(16:53) - Psychedelics v. Antidepressants
(20:25) - MDMA v. Psylocibin
(20:36) - What happens in the brain on psychedelics?
(25:01) - Micro v. Macro-dosing
(28:35) - Women's Health and Psychedelics
(34:32) - Female Hormones
(36:56) - Menopause
(38:22) - Eating disorders
(41:32) - Post-partum depression & Moms Who Mushroom
(47:04) - Words of caution
(52:11) - Other research Nina is interested in
(57:06) - The Future of Medicine
Links:
Nina's Notes - https://www.notes.ninapatrick.xyz
Edition about Psychedelics and Women's Health - https://www.notes.ninapatrick.xyz/p/48-what-we-know-about-the-effect
Edition about the Future of Medicine (Med3) - https://www.notes.ninapatrick.xyz/p/46-med3
Champalimaud Center of the Unknown - https://www.fchampalimaud.org/champalimaud-foundation/champalimaud-centre

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