8 episodes

Pharmanipulation explores how industry markets not only drugs, but diseases, and exposes ineffective or harmful practices in medicine. This series takes an evidence-based, edgy, and entertaining approach to health and medicine. Each episode features an interview with topic experts and provides resources to learn more about how the pharmaceutical and medical device industries influence medical knowledge and public health. Pharmanipulation is a podcast by PharmedOut, a rational prescribing project at Georgetown University Medical Center, directed by Dr. Adriane Fugh-Berman.

Pharmanipulation PharmedOut

    • Health & Fitness
    • 5.0 • 8 Ratings

Pharmanipulation explores how industry markets not only drugs, but diseases, and exposes ineffective or harmful practices in medicine. This series takes an evidence-based, edgy, and entertaining approach to health and medicine. Each episode features an interview with topic experts and provides resources to learn more about how the pharmaceutical and medical device industries influence medical knowledge and public health. Pharmanipulation is a podcast by PharmedOut, a rational prescribing project at Georgetown University Medical Center, directed by Dr. Adriane Fugh-Berman.

    Ep. 8 - "The First One's Free and Then You're Hooked: The Problem with Free Drug Samples" with Dr. Shahram Ahari

    Ep. 8 - "The First One's Free and Then You're Hooked: The Problem with Free Drug Samples" with Dr. Shahram Ahari

    Episode 8 features an interview with Shahram Ahari MD, an emergency medicine physician and former drug rep, that explores the world of pharmaceutical samples. We chat about why samples are the most important marketing tactic drug companies have, how samples are used to manipulate prescribing choices, and discuss whether or not drug samples should be banned.

    Pharmanipulation is produced by PharmedOut, a project at Georgetown University Medical Center that advances evidence-based prescribing.

    Additional Resources

    PharmedOut fact sheet on drug samples: ⁠https://georgetown.app.box.com/s/y51hkdvu2dju9sv26fjcc976ivlvwtkj

    Summaries of key articles on the topic of drug samples: ⁠https://georgetown.app.box.com/s/3052cjlgv9thfw0qf3k9fkuyio978mbr

    PharmedOut’s paper “Pharmaceutical marketing: the example of drug samples.” Link: https://joppp.biomedcentral.com/articles/10.1186/s40545-022-00479-z

    PharmedOut’s paper “Following the Script: How Drug Reps Make Friends and Influence Doctors.” Link: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0040150

    PharmedOut’s paper “Why lunch matters: Assessing physicians' perceptions about industry relationships.” Link: https://onlinelibrary.wiley.com/doi/abs/10.1002/chp.20081

    Dr. Ahari’s op-ed in The Washington Post “I was a drug rep. I know how pharma companies pushed opioids.” Link: https://www.washingtonpost.com/outlook/i-was-a-drug-rep-i-know-how-pharma-companies-pushed-opioids/2019/11/25/82b1da88-beb9-11e9-9b73-fd3c65ef8f9c_story.html

    • 31 min
    Ep. 7 – “Rethinking mild cognitive impairment and dementia" with Dr. Peter Whitehouse and Dr. Lon Schneider

    Ep. 7 – “Rethinking mild cognitive impairment and dementia" with Dr. Peter Whitehouse and Dr. Lon Schneider

    Episode 7 features an interview with Peter Whitehouse MD, PhD and Lon Schneider MD, MS exploring dementia and mild cognitive impairment. We chat about the medicalization of normal aging, the overdiagnosis of mild cognitive impairment, problems with new drugs and tests for Alzheimer’s disease, and how to prevent dementia. 

    Pharmanipulation is produced by PharmedOut, a project at
    Georgetown University Medical Center that advances evidence-based prescribing.

    Additional Resources

    PharmedOut resources on Alzheimer’s and Mild Cognitive
    Impairment: https://sites.google.com/georgetown.edu/pharmedout/advocacy/alzheimers-and-mild-cognitive-impairment?authuser=0


    Dementia prevention, intervention, and care: 2020 report of
    the Lancet Commission. Link: https://www.thelancet.com/article/S0140-6736(20)30367-6/fulltext


    Making the Case for Accelerated Withdrawal of Aducanumab.
    Link: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad220262


    Dr. Peter Whitehouse’s latest letter to the editor, “Cummings
    column on Alzheimer treatments skips over a few key things.” Link: https://www.cleveland.com/letters/2023/10/cummings-column-on-alzheimer-treatments-skips-over-a-few-key-things.html


    American Dementia: Brain Health in an Unhealthy Society
    by Danny George PhD and Peter Whitehouse MD, PhD. Link: https://www.press.jhu.edu/books/title/12394/american-dementia


    The Myth of Alzheimer’s: What You Aren't Being
    Told About Today's Most Dreaded Diagnosis by Peter Whitehouse MD, PhD and Danny George MSc. Link: https://us.macmillan.com/books/9780312368173/themythofalzheimers

    • 42 min
    Ep. 6 – "Fat and fiction" Considering the risks and benefits of weight loss and weight loss drugs with Ragen Chastain and Dr. Joel Lexchin

    Ep. 6 – "Fat and fiction" Considering the risks and benefits of weight loss and weight loss drugs with Ragen Chastain and Dr. Joel Lexchin

    Episode 6 invites Ragen Chastain, activist and author, and Joel Lexchin MD of York University, to discuss myths about weight and health, the hype around Ozempic and Wegovy, and the unclear connection between weight loss and health. 

    Pharmanipulation is produced by PharmedOut, a project at Georgetown University Medical Center that advances evidence-based prescribing.

    To learn more about Ragen Chastain and her work, please visit her website: https://weightandhealthcare.substack.com/

    Additional Resources

    Dances With Fat Monthly Workshop – September: Navigating Weight Stigma at the Doctor’s Office date changed from September 27 to October 11 to avoid overlap with ASDAH’s annual meeting. Link: https://danceswithfat.org/monthly-online-workshops/ 

    Books

    “Fearing the Black Body: The Racial Origins of Fat Phobia”
    by Sabrina Strings. Link: https://nyupress.org/9781479886753/fearing-the-black-body/

    “Belly of the Beast: The Politics of Anti-Fatness as
    Anti-Blackness” by Da'Shaun L. Harrison. Link: https://www.penguinrandomhouse.com/books/670607/belly-of-the-beast-by-dashaun-harrison/

    Articles

    "Semaglutide: a new drug for the treatment of obesity" by Joel Lexchin and Barbara Mintzes. Drug Ther Bull. 2023 Oct 25:dtb-2023-000007. doi: 10.1136/dtb.2023.000007. Link: https://pubmed.ncbi.nlm.nih.gov/37879878/

    “How the ‘It's Bigger Than Me’ Campaign Is Harming Fat People for Profit" by Ragen
    Chastain. Link: https://themighty.com/topic/eating-disorders/its-bigger-than-me-campaign-harms-fat-people-for-profit/ 

    “Weighing the Consequences of Weight-Loss Drugs” by Judy
    Butler and Dr. Adriane Fugh-Berman. Link: https://www.medpagetoday.com/opinion/second-opinions/104482

    Igho J. Onakpoya, Carl J. Heneghan and Jeffrey K. Aronson. Post-marketing withdrawal of anti-obesity medicinal products because of adverse drug reactions: a systematic review. BMC Medicine 2016;14:191. Link: https://pubmed.ncbi.nlm.nih.gov/27894343/

    Prescrire’s "Semaglutide (Wegovy°) for excess body
    weight" Prescrire International 2023; 32 (245): 36-38. Link: https://english.prescrire.org/en/81/168/66102/0/NewsDetails.aspx

    Please note: the full article is available for subscribers
    only.

    PharmedOut is supported primarily by individual
    donations. To donate, please visit: https://sites.google/com/georgetown.edu/pharmedout/donate

    • 33 min
    Ep. 5 – “Under the Knife and Over it” Unnecessary C-sections and hysterectomies with Dr. Tony Scialli

    Ep. 5 – “Under the Knife and Over it” Unnecessary C-sections and hysterectomies with Dr. Tony Scialli

    Episode 5 invites Tony Scialli MD, an obstetrician-gynecologist and reproductive toxicologist, to talk about the overuse of gynecologic surgeries – namely hysterectomies and Cesarean sections.


    Pharmanipulation is produced by PharmedOut, a Georgetown University Medical Center rational prescribing project. For a transcript of this episode, please visit: https://georgetown.box.com/s/1bdbxvaezezlpu0qsm02q3101mmhsi3a

    To learn more about Dr. Tony Scialli, please visit his website:
    https://www.scialliconsulting.com/#about

    Additional Resources

    The Cultural Warping of Childbirth by Doris Haire. Link:
    https://www.abebooks.com/9789315600471/Cultural-Warping-Childbirth-Doris-Haire-9315600479/plp

    Our Bodies, Ourselves by Boston Women’s Health Collective.
    Link: https://www.simonandschuster.com/books/Our-Bodies-Ourselves/Boston-Womens-Health-Book-Collective/9781439190661

    Spiritual Midwifery by Ina May Gaskin. Link: https://www.abebooks.com/servlet/BookDetailsPL?bi=31385160493&ref_=ps_ggl_17730880232&cm_mmc=ggl-_-US_Shopp_Trade_10to20-_-product_id=COM9781570671043USED-_-keyword=&gclid=Cj0KCQjw1_SkBhDwARIsANbGpFs4ExX1P9YXQFUuTueJytlUy2VdelLMIBU7neywgGu14aYawh1w7hkaArxfEALw_wcB
    National Women’s Health Network. Link: https://nwhn.org/

    PharmedOut is supported primarily by individual donations.
    To donate, please visit: https://sites.google/com/georgetown.edu/pharmedout/donate

    • 28 min
    Ep. 4 - "How Do We Know We are Sick? Culture, Disease and Illness" with Dr. Sylvia Önder and Dr. Yulia Chentsova Dutton

    Ep. 4 - "How Do We Know We are Sick? Culture, Disease and Illness" with Dr. Sylvia Önder and Dr. Yulia Chentsova Dutton

    Episode 4 invites medical anthropologist Sylvia Önder PhD and cultural psychologist Yulia Chentsova Dutton PhD to discuss the differences among disease, sickness and illness and explore the concepts of invented diseases, folk illnesses, and the social value of certain diseases. 

    Pharmanipulation is produced by PharmedOut, a Georgetown University Medical Center rational prescribing project. For a transcript of this episode, please visit: https://georgetown.box.com/s/ufrrmreu5d26cbfvorbu863uz32qkih9

    PharmedOut Conference: https://sites.google.com/georgetown.edu/pharmedout/resources/conferences/2023-conference

    Bonnie O’Connor. Healing Traditions: Alternative Medicine and the Health Professions. 1995. Link: https://www.jstor.org/stable/j.ctt3fhvd3

    Irving Zola. Medicine as an institution of social control. 1976. Link: https://www.jstor.org/stable/43618673

    Michel Foucault. The Birth of the Clinic: An Archaeology of Medical Perception. Link: https://www.penguinrandomhouse.com/books/55034/the-birth-of-the-clinic-by-michel-foucault/ 

    PharmedOut is supported primarily by individual donations. To donate, please visit: https://sites.google/com/georgetown.edu/pharmedout/donate

    • 42 min
    Ep. 3 - "Paying Attention to ADHD: Diagnosis and Treatment in Children" with Dr. Gretchen LeFever Watson and Robert Whitaker

    Ep. 3 - "Paying Attention to ADHD: Diagnosis and Treatment in Children" with Dr. Gretchen LeFever Watson and Robert Whitaker

    Episode 3 of Pharmanipulation invites Gretchen LeFever Watson PhD and Robert Whitaker to question diagnoses of attention deficit hyperactivity disorder and to critique drug treatment of behaviors associated with ADHD.

    Pharmanipulation is produced by PharmedOut, a Georgetown University Medical Center rational prescribing project. For a transcript of this episode, please visit: https://georgetown.box.com/s/jjei0u9zhtezfqg2i5p83h9per8nzugc



    For a list of resources and studies mentioned in this episode, please visit: ⁠https://bit.ly/Ep3Resources



    To learn more about Dr. LeFever Watson, please visit her website: https://drgretchenwatson.com/

    To learn more about Robert Whitaker, please visit his website: https://www.madinamerica.com/robert-whitaker-new/ 



    PharmedOut is supported primarily by individual donations. To donate, please visit: https://sites.google/com/georgetown.edu/pharmedout/donate

    • 40 min

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