The MicrobiomeResearchX (MRX) Podcast Adarsh Sandhu

Our guest today is Christoph A. Thaiss the Microbiology Department of the Perelman School of Medicine at the University of Pennsylvania, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "A microbiome exercise: gut-brain connections drive the motivation to work out.”  
Details about the prize-winning essay
https://www.science.org/doi/10.1126/science.adi6329
Essay: A microbiome exercise
Science, 381, 6653, p. 38, 2023. 
DOI: 10.1126/science.adi6329


Related research 
L. Dohnalová et al A microbiome-dependent gut-brain pathway regulates motivation for exercise. 
Nature, 612(7941):739-747, 2022. 
DOI: 10.1038/s41586-022-05525-z. E

Our guest today is Christopher Stewart of the Translational and Clinical Research Institute at Newcastle University, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Diet-microbe-host interaction in early life: breastmilk bioactives are important to infant microbiome.”  
Details about the prize-winning essay
https://www.science.org/doi/10.1126/science.adi6318
Essay: Diet-microbe-host interaction in early life
Science, 381, 6653, p. 38, (2023)
DOI: 10.1126/science.adi6318


Related research 
C. J Stewart et al, Temporal development of the gut microbiome in early childhood from the TEDDY study. 
Nature 562 (7728): 583-588, (2018). 
DOI: 10.1038/s41586-018-0617-x. 

Our guest today is Sara Clasen of the Max Planck Institute for Biology in Tübingen, Germany, who is the recipient of the 2023 NOSTER & Science Microbiome Grand Prize for her essay entitled, “The sound of silence”. 
Details about the prize-winning essay
https://www.science.org/content/page/2023-noster-science-prize-winners
Essay: The sound of silence
Science, 381, 6653, pp. 37-38,  2023
DOI: 10.1126/science.adi6265


Related research 
Clasen SJ, Bell MEW, Borbón A, Lee DH, Henseler ZM, de la Cuesta-Zuluaga J, Parys K, Zou J, Wang Y, Altmannova V, Youngblut ND, Weir JR, Gewirtz AT, Belkhadir Y, Ley RE. 
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor-5. 
Sci Immunol. 2023 Jan 6;8(79):eabq7001.
doi: 10.1126/sciimmunol.abq7001

Our guest today is Jennifer Hampton Hill, University of Utah is the recipient of the 2022 NOSTER & Science Microbiome Grand Prize for her work that “revealed that the resident microbiome is a promising source of previously undiscovered modulators of host β cells.”
Links to details about the prize-winning essay
https://www.science.org/content/page/2022-noster-science-prize-winners
Essay: From bugs to β cells
SCIENCE, 7 Jul 2022, Vol 377, Issue 6602, pp. 164-165 DOI: 10.1126/science.abq6051
https://www.science.org/doi/10.1126/science.abq6051
Latest research 
Jennifer Hampton Hill, Michelle Sconce Massaquoi, Emily Goers Sweeney, Elena S. Wall, Philip Jahl, Rickesha Bell, Karen Kallio, Daniel Derrick, L. Charles Murtaugh, Raghuveer Parthasarathy, S. James Remington, June L. Round, Karen Guillemin
 
BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
 
Cell Metabolism, 34, pp. 1779-1791.e9, (2022)
https://doi.org/10.1016/j.cmet.2022.09.001.
 
https://www.sciencedirect.com/science/article/pii/S1550413122003916
 
Media Coverage 
U OF U HEALTH POSTDOCTORAL FELLOW EARNS PRESTIGIOUS NOSTER AND SCIENCE MICROBIOME PRIZE
https://uofuhealth.utah.edu/newsroom/news/2022/07/hill-noster-science-prize
 
Jumpstarting insulin production with microbial diversity wins NOSTER & Science Microbiome Prize
https://www.eurekalert.org/news-releases/957641
 
MRX website
https://noster-mrx.net/
2022 NOSTER & Science Microbiome Prize: Noster Inc and AAAS announce the grand winner and finalists of the 2022 NOSTER & Science Microbiome Prize
https://noster-mrx.net/post/700075484746317824/news-and-events
 

Our guest today is Erez Baruch, who recently started an internal medicine residency in a research (Physician-Scientist) track to medical oncology. Internal medicine training is conducted at the McGovern Medical School in Houston, Texas.
Erez is a finalist of the 2021 NOSTER & Science Microbiome Prize for his essay, "Microbiota modulation to fight cancer”, based on his research on “mechanisms of immunotherapy resistance and toxicity, modulation of the gut microbiota, and interaction between innate and adaptive immune cells”. 
Links to details about the prize-winning essay are available on the Noster Inc MicrobiomeResearchX (MRX) website and related AAAS Science sites.
MRX 
https://noster-mrx.net/
Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners 
https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-disease
Essay by Erez Baruch
https://www.science.org/doi/full/10.1126/science.abi9360

Our guest today is Maria Zimmermann-Kogadeeva, who started her lab in the Genome Biology Unit at EMBL Heidelberg in 2021.
Maria is a finalist of the 2021 NOSTER & Science Microbiome Prize for her essay, "Quantifying host-microbiota interactions” based on her research on the adaptation and consequences of microbes to their surroundings in hosts.
Links to details about the prize-winning essay are available on the Noster Inc MicrobiomeResearchX (MRX) website and related AAAS Science sites.
https://noster-mrx.net/
Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners 
https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-disease
Essay by Maria Zimmermann-Kogadeeva
https://www.science.org/doi/full/10.1126/science.abi9357