Until the Brown family arrived last year, it seemed like nothing ever changed in Everwood, a charming little town in the Rocky Mountains of Colorado. Dr. Andrew "Andy" Brown has made the transition from a world-renowned neurosurgeon, whose career overshadowed his parental obligations, to a small-town clinician and attentive but struggling father to bright 10-year-old Delia and troubled 16-year-old Ephram. Plainspoken Edna Harper (series star Debra Mooney) serves as Dr. Brown's nurse and office manager, despite being the mother of the only other doctor in town, irascible Dr. Harold Abbott, whose children, 16-year-old Amy (series star Emily VanCamp) and 18-year-old Bright (series star Chris Pratt), have become friends with Dr. Brown's at school. Dr. Brown has also found his neighbor, Nina Feeney (series star Stephanie Niznik), to be a reliable confidante. And the school bus driver, Mr. Irv Harper (series star John Beasley), keeps watch over it all.
Dr. Brown is concerned that Ephram needs more extracurricular activities in order to be accepted at a top college, but Ephram is only focused on his Juilliard music school audition--which has surprising results. Amy's lack of interest in college preparation alarms her mother, Rose (recurring guest star Merrilyn Gann), more than her father, Dr. Abbott. And Bright's poor grades result in him being ejected from the football team, possibly jeopardizing the scholarship his father believes may be Bright's only chance to get into a decent school. Meanwhile, Dr. Brown tries to help a cheerleader, Stacey Wilson (Kristen Bell), who has ruptured breast implants but cares more about looking good than being healthy.
The entire Abbott family is agitated by the return of Dr. Linda Abbott (recurring guest star Marcia Cross - "Melrose Place"), Dr. Abbott's sister, who has been practicing Eastern-based medicine in exotic locations around the world. Edna is so proud of her daughter's accomplishments that she doesn't notice how lonely Linda is, and Edna needs to be reminded what a wonderful life she's built with Irv, even without travel and excitement. Linda encounters major resistance from Dr. Abbott when she announces her decision to join his practice. Meanwhile, Dr. Brown learns that some local adolescents may be practicing unsafe sex, and he is shocked at their parents' reaction to the situation. Also, Bright asks Ephram to watch over Amy, whose odd behavior has everyone worried.
Dr. Brown's well-intentioned plan to give Ephram more free time by hiring college student Madison Kellner (recurring guest star Sarah Lancaster) as a caretaker for Delia ends up making things worse. Madison treats Ephram like a child and embarrasses him in front of Amy. Meanwhile, Dr. Brown's concern for the deceased Colin's alcoholic father, James (recurring guest star Michael Flynn), distracts him from Nina's struggle with her divorce proceedings. Dr. Abbott continues to clash with his physician sister, Linda (recurring guest star Marcia Cross), when she tries to take over his office. The differences in their personalities and medical philosophies become alarmingly clear.
When Dr. Brown invites Linda (recurring guest star Marcia Cross) to dinner at the Brown house to discuss a patient, Delia lashes out, using foul language. With some insight from Delia's caretaker, Madison Kellner (recurring guest star Sarah Lancaster), Ephram figures out the reason for his sister's bad behavior. Meanwhile, Amy's depression deepens, but when her therapist recommends medication, Dr. Abbott refuses to write a prescription to help his daughter cope with Colin's death.
Much to his chagrin, Dr. Abbott suspects that Linda (recurring guest star Marcia Cross) and Dr. Brown are far too attracted to each other, so he decides to select more appropriate suitors for his sister. Meanwhile, Ephram finally has the courage to tell Amy how he really feels about their relationship, but he is confused by his interest in Madison (recurring guest star Sarah Lancaster), who comes to his aid when Ephram needs help passing his driving test. Dr. Brown tries to help the soon-to-be-remarried Reverend Keyes (Tim DeKay - "Carnivale") cope with his impending blindness, but the minister would rather leave his fate to God than attempt a new treatment that might save his sight.
Treat Williams
Dr. Andrew Brown
Gregory Smith
Ephram Brown
Emily VanCamp
Amy Abbott
Debra Mooney
Edna Abbott
John Beasley
Irv Harper